Yesterday I made my longest shot on a groundhog so far, 446 yards. My previous was 416 earlier this spring. I've also killed them at 360 and 400 this spring. My rifle is a 22-250 Savage Model 12FVSS in a Stockade Elk Stalker stock with a Leupold VX3 6.5-20 with a varmint hunter reticle. I load 55gr Sierra Gamekings over 36.0 grains of Varget. This rifle shoots them very well. I missed a groundhog at 450 yards (same spot) last year so I set up a target there to learn my hold. I didn't miss this time .